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      Nicholas Bustos

      Intramural Research Trainee at NIH.

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C. Elegans beta(pat-3) Integrins phenotyping through RNAi

14 Oct 2016

C. Elegans beta(pat-3) phenotyping through RNAi

Myeongwoo Lee Lab for Developmental Genetics at Baylor working as an undergraduate research assistant to understand the specifics of overlapping pathways and cell messengers involved in cell(DTC) migration and proliferation in C. elegans. Carried out reverse and forward genetic analysis to characterize UNC-54 and other mutants and the effects of RNAi on integrins (beta-pat3) on ECM interactions. Became proficient with RNAi, immunohistochemistry, ELISA and worm handling. This experience allowed me to connect the biochemical dots from signal transduction to animal behavior using molecular and computational tools.

“Progress in science depends on new techniques, new discoveries, and new ideas, probably in that order” -Sydney Brenner





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